Submitted for Publication: December 2, 2010; final revision received April 14, 2011; accepted April 18, 2011.
Published Online: July 11, 2011. doi:10.1001/archophthalmol.2011.179
Financial Disclosure: None reported.
Funding/Support: This study was supported by the National Institutes of Health (grants EY011751 and EY018810) and by Research to Prevent Blindness, New York (Dr Holmes, as Olga Keith Weiss Scholar, and an unrestricted grant to the Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota).
Role of the Sponsors: The funding organizations did not participate in the design and conduct of the studies; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript. The National Institutes of Health provided external oversight through an independent data and safety monitoring committee.
Online-Only Material: This article is featured in the Archives Journal Club. Go here to download teaching PowerPoint slides.