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A Report of High Intraocular Pressure With the Dexamethasone Intravitreal Implant—Reply

Careen Lowder, MD, PhD; Ruben Belfort, MD; Sue Lightman, MD; C. Stephen Foster, MD; Michael R. Robinson, MD; Rhett M. Schiffman, MD, MS, MHSA; Xiao-Yan Li, MD; Harry Cui, MS; David A. Hollander, MD, MBA; Yehia Hashad, MD; Scott M. Whitcup, MD
Arch Ophthalmol. 2011;129(12):1638-1640. doi:10.1001/archophthalmol.2011.356.
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Dr Saraiya and colleagues describe a patient with bilateral idiopathic chronic iridocyclitis with multifocal choroiditis and persistent cystoid macular edema despite maximally tolerated systemic immunosuppression. In addition, the patient, a known “steroid responder,” was being treated with topical prednisone acetate ophthalmic suspension (Pred Forte; Allergan, Irvine, California) twice daily and topical brimonidine tartrate–timolol maleate twice daily in both eyes. The patient received dexamethasone intravitreal implants (Ozurdex; Allergan, Irvine, California) in the left eye and then in the right eye 3 weeks later, with rapid resolution of cystoid macular edema. Within 2 months after the initial injection, the patient developed elevated intraocular pressure (IOP) in both eyes that continues despite receiving 4 topical IOP-lowering medications and oral methazolamide.


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December 1, 2011
Nehali Vira Saraiya, MD; Sarju S. Patel, MD, MPH; Debra A. Goldstein, MD
Arch Ophthalmol. 2011;129(12):1638-1640. doi:10.1001/archophthalmol.2011.355.
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