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Research Letters | July 2012

Intravitreal Bevacizumab in Advanced-Stage Neovascular Age-Related Macular Degeneration With Visual Acuity Lower Than 20/200

Maurizio Battaglia Parodi, MD; Marialucia Cascavilla, MD; Alexandros Papayannis, MD; Dimitrios Stelios Kontadakis, MD; Francesco Bandello, MD; Pierluigi Iacono, MD

Arch Ophthalmol. 2012;130(7):934-935. doi:10.1001/archophthalmol.2011.2617.

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Although intravitreal anti–vascular endothelial growth factor has greatly improved the management of subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration,¹^- 4 little is known regarding the effects in more advanced stages associated with low visual acuity. We designed a randomized clinical trial to address this subject.

Correspondence: Dr Iacono, Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Via Olgettina, 60, 20132, Milano, Italy (pierluigi.iacono@libero.it).

Author Contributions: Dr Iacono had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Financial Disclosure: None reported.

Trial Registration: clinicaltrials.gov Identifier: NCT01327222

Previous Presentation: This paper was presented in part at the 34th Annual Meeting of the Macula Society; March 10, 2011; Boca Raton, Florida.

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Figure 1. Mean best-corrected visual acuity (BCVA) values during the 6-month follow-up.

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Figure 2. Mean central macular thickness (CMT) values during the 6-month follow-up.

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Parodi M, Cascavilla M, Papayannis A, Kontadakis D, Bandello F, Iacono P. Intravitreal Bevacizumab in Advanced-Stage Neovascular Age-Related Macular Degeneration With Visual Acuity Lower Than 20/200. Arch Ophthalmol. 2012;130(7):934-935. doi:10.1001/archophthalmol.2011.2617.

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