Aug 2012, Vol 130, No. 8 >

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Research Letters | Aug 2012

Morning Glory Disc Anomaly in Association With Ipsilateral Optic Nerve Glioma

Pratiti Bandopadhayay, MBBS, FRACP; Linda Dagi, MD; Nathan Robison, MD; Liliana Goumnerova, MD; Nicole J. Ullrich, MD, PhD

Arch Ophthalmol. 2012;130(8):1082-1083. doi:10.1001/archophthalmol.2012.412.

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Morning glory disc anomaly (MGDA) is typically a unilateral congenital disorder characterized by the funnel-shaped excavation of an enlarged optic disc. Retinal vessels emanate radially beyond a central white core, and the disc itself is encircled by an elevated region of chorioretinal pigmentation. Serous and, less commonly, rhegmatogenous retinal detachment may coexist.¹ Infants with MGDA often manifest strabismus or leukokoria. Morning glory disc anomaly is associated with other midline developmental or vascular malformations. We describe a patient with MGDA and concurrent ipsilateral optic nerve glioma.

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Figure 1. Fundus photograph of the right eye demonstrating morning glory disc anomaly with a central glial tuft, a radially oriented pattern of emergence of retinal vessels, and retinal detachment.

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Figure 2. Axial (A) and coronal (B) T2-weighted fluid-attenuated inversion recovery magnetic resonance images of the orbits with fat saturation enlargement along the right prechiasmatic optic nerve. C, After gadolinium enhancement, there is minimal linear enhancement of the outer portion of the lesion. Arrows indicate optic nerve.

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Bandopadhayay P, Dagi L, Robison N, Goumnerova L, Ullrich NJ. Morning Glory Disc Anomaly in Association With Ipsilateral Optic Nerve Glioma. Arch Ophthalmol. 2012;130(8):1082-1083. doi:10.1001/archophthalmol.2012.412.

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