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Ophthalmic Images | Aug 2012

Anterior Segment Spectral-Domain Optical Coherence Tomography Findings in Cystinosis

Benoit Guignier, MD; Ines Samet, MD; Tristan Bourcier, MD, PhD
Arch Ophthalmol. 2012;130(8):1018. doi:10.1001/archophthalmol.2012.32.
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A 45-year-old woman was referred for a 10-year history of blurry vision and photophobia. Slitlamp examination showed bilateral corneal deposits (Figure, A and B). Best-corrected visual acuity was 20/25 in both eyes. Spectral-domain optical coherence tomography with an anterior segment module revealed hyperreflective deposits disseminated in the corneal stroma and endothelium that might correspond to cystine crystals (Figure, C). Systemic workup findings (kidney, thyroid, and liver) were negative. To our knowledge, this is the first report of spectral-domain optical coherence tomography performed in cystinosis.
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A 45-year-old woman was referred for a 10-year history of blurry vision and photophobia. Slitlamp examination showed bilateral corneal deposits (Figure, A and B). Best-corrected visual acuity was 20/25 in both eyes. Spectral-domain optical coherence tomography with an anterior segment module revealed hyperreflective deposits disseminated in the corneal stroma and endothelium that might correspond to cystine crystals (Figure, C). Systemic workup findings (kidney, thyroid, and liver) were negative. To our knowledge, this is the first report of spectral-domain optical coherence tomography performed in cystinosis.

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