In July 2010, a 68-year-old woman without pertinent medical or ocular history visited our uveitis clinic because of decreased vision and floaters bilaterally for 5 days. Two weeks prior, she was bitten by a dog and was prescribed prophylactic levofloxacin. After 4 days of therapy, she noted painless bilateral palmar macules and pustules, followed a day later by blurred vision and floaters in both eyes. She discontinued levofloxacin and was referred to us. Other long-term medications she had been receiving at the time of the initial visit included atenolol, amlodipine besylate, rabeprazole sodium, diphenhydramine hydrochloride, and low-dose aspirin; however, none of these represented a new exposure. Further, the patient was bitten by her own dog whose immunizations were up to date, so rabies vaccination was not necessary.