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Retinal Necrosis Following Varicella-Zoster Vaccination

John A. Gonzales, MD; Ashleigh L. Levison, MD; Jay M. Stewart, MD; Nisha R. Acharya, MD, MS; Todd P. Margolis, MD, PhD
Arch Ophthalmol. 2012;130(10):1355-1356. doi:10.1001/archophthalmol.2012.2255.
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We read with interest the recent article by Charkoudian et al1 describing 2 cases of acute retinal necrosis following vaccination with Zostavax and wish to share our own experience of zoster retinitis following vaccination with Varivax (varicella virus vaccine, live; Merck & Co, Inc). Our case is unique, however, in that we identified the vaccine strain of the virus (Oka) in the vitreous of the involved eye.

Correspondence: Dr Gonzales, F. I. Proctor Foundation, University of California, San Francisco, 95 Kirkham St, San Francisco, CA 94143 (john.gonzales@ucsf.edu).

Financial Disclosure: None reported.

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Figure 1. Fundus photograph of the right eye showing extensive peripheral retinal necrosis.

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Figure 2. Fundus photograph of the left eye showing the focus of retinitis inferotemporal to the macula.




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