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Research Letters | Dec 2012

Evolving Fluoroquinolone Resistance Among Coagulase-Negative Staphylococcus Isolates Causing Endophthalmitis

Andrew M. Schimel, MD; Darlene Miller, DHSc; Harry W. Flynn, MD

Arch Ophthalmol. 2012;130(12):1617-1618. doi:10.1001/archophthalmol.2012.2348.

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Endophthalmitis is a serious, sight-threatening condition resulting in substantial morbidity. With the widespread use of fluoroquinolone antibiotic eyedrops as a prophylactic agent, there is concern regarding increased frequency of fluoroquinolone resistance. We report the evolution of fluoroquinolone resistance among coagulase-negative Staphylococcus endophthalmitis isolates at the Bascom Palmer Eye Institute.

Correspondence: Dr Flynn, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL 33136 (hflynn@med.miami.edu).

Conflict of Interest Disclosures: None reported.

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Figure. Percentage of fluoroquinolone-resistant coagulase-negative Staphylococcus isolates causing endophthalmitis at the Bascom Palmer Eye Institute during the past 21.5 years. Data are divided by each fluoroquinolone antibiotic.

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Schimel AM, Miller D, Flynn HW. Evolving Fluoroquinolone Resistance Among Coagulase-Negative Staphylococcus Isolates Causing Endophthalmitis. Arch Ophthalmol. 2012;130(12):1617-1618. doi:10.1001/archophthalmol.2012.2348.

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