We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Letters |

Lichen Simplex Chronicus of the Conjunctiva

Heather D. Potter, MD; Vivian Lee, MD; Molly A. Hinshaw, MD; Sherif S. Khedr, MD; Daniel M. Albert, MD; Cat N. Burkat, MD
JAMA Ophthalmol. 2013;131(6):816-818. doi:10.1001/jamaophthalmol.2013.1890.
Text Size: A A A
Published online


Lichen simplex chronicus (LSC) is a disorder commonly encountered by dermatologists, caused by constant rubbing of the skin that clinically induces thickening and lichenification. While a case report of LSC of the eyelids has been published,1 a careful search of the literature did not disclose any prior case of LSC of the palpebral conjunctiva.

Correspondence: Dr Lee, Scheie Eye Institute, University of Pennsylvania, 51 N 39th St, Scheie Room 620, Philadelphia, PA 19104 (vivian.lee@uphs.upenn.edu).

Published Online: April 4, 2013. doi:10.1001/jamaophthalmol.2013.1890

Conflict of Interest Disclosures: None reported.

Funding/Support: This work was supported by grant P30-EY016665 (Core Grant for Vision Research) from the National Institutes of Health and an unrestricted department award from Research to Prevent Blindness.

Additional Contributions: We are grateful for the support from the McPherson Eye Research Institute, University of Wisconsin.

Figures in this Article


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Graphic Jump Location

Figure 1. Slitlamp photograph of the patient's everted left upper eyelid reveals a thickened and keratinized palpebral conjunctiva.

Place holder to copy figure label and caption
Graphic Jump Location

Figure 2. Elliptical incisional biopsy of the left palpebral conjunctiva demonstrates microscopically a metaplastic conjunctiva showing significant acanthosis, orthokeratosis, and parakeratosis with squamatization. Chronic nongranulomatous inflammation is present in the substantia propria (hematoxylin-eosin, original magnification ×200).




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.