Metastasis to the contralateral orbital cavity in uveal melanoma (UM) is extremely rare.1 Only 8 cases of such metastases have been reported, and none included mutational analysis. For the first time, to our knowledge, we report data from a mutational analysis of GNAQ and GNA11 supporting the diagnosis of a single metastatic tumor.
Correspondence: Dr Böhm, Department of Ophthalmology, University Hospital of Muenster, Albert Schweitzer Campus D1, Bldg D15, 48149 Muenster, Germany (firstname.lastname@example.org).
Published Online: April 9, 2013. doi:10.1001/jamaophthalmol.2013.1921
Author Contributions: Drs Böhm and Tsianakas share first authorship.
Conflict of Interest Disclosures: None reported.
Additional Contributions: The manuscript was edited by English Science Editing, Auckland, New Zealand. Solon Thanos, MD, PhD, provided comments that greatly improved the manuscript.