Research Letter |

Oral Glucosamine Supplements as a Possible Ocular Hypertensive Agent

Ryan K. Murphy, DO, MA1; Lecea Ketzler, DO1; Robert D. E. Rice, MD2; Sandra M. Johnson, MD3; Mona S. Doss, MA1; Edward H. Jaccoma, MD1
[+] Author Affiliations
1University of New England College of Osteopathic Medicine, Biddeford, Maine
2Associated Eyecare, Sanford, Maine
3Department of Ophthalmology, University of Virginia, Charlottesville
JAMA Ophthalmol. 2013;131(7):955-957. doi:10.1001/jamaophthalmol.2013.227.
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The Centers for Disease Control and Prevention report that osteoarthritis affects 27 million adults in the United States. Glucosamine sulfate is a naturally occurring substance found in human cartilage and a precursor for glycosaminoglycans (GAGs). A combination of supplements, glucosamine and chondroitin sulfate, was shown in the Glucosamine/Chondroitin Arthritis Intervention Trial to aid moderate to severe osteoarthritic knee pain.1

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Intraocular Pressure Before, During, and After Glucosamine Supplementation

Intraocular pressure (IOP) from patients in cohort A (n = 11) (A), cohort B (B), and cohorts A and B combined (C) before glucosamine (V), during glucosamine supplementation (Gl), and after discontinuing glucosamine (D/C).

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