On fundus autofluorescence imaging, 16 lesions were homogeneously hyperautofluorescent and 1 was homogeneously hypoautofluorescent with a hyperautofluorescent halo. Thirteen of 17 SC lesions had adequate infrared reflectance imaging and EDI-OCT. Of these, the lesions were hyperreflective (n = 11) or hyporeflective (n = 2) on infrared reflectance imaging. On EDI-OCT, all lesions originated within the sclera with thinning or absence of the overlying choroid (mean thickness, 28 μm; range, 0-119 μm) (Table 1 and Table 2). The lesions were elevated with undulating contour (n = 11) or flat (n = 2). The anterior scleral surface was irregular and “rocky” (n = 5) (Figure) or smooth and “rolling” (n = 8). The lesions were moderately reflective (n = 10) with bright anterior band (n = 3). The posterior margin of the lesion, and therefore the thickness, could not be identified in any case. By EDI-OCT, the mean diameter was 3689 μm (range, 2345-5804 μm). Overlying features included outer nuclear layer thinning (n = 2), external limiting membrane disruption (n = 1), inner segment–outer segment junction absence (n = 2), subretinal fluid (n = 1), retinal pigment epithelium alteration (n = 4), and pigment epithelial detachment (n = 1).