We describe spectral-domain optical coherence tomography (OCT; Heidelberg Spectralis) imaging of 3 patients with Niemann-Pick disease type B. This expands the range of previously reported anatomical correlates of the ophthalmoscopic macular halo surrounding the “cherry-red spot.”1
Article InformationCorresponding Author: Scott E. Brodie, MD, PhD, Department of Ophthalmology, Mount Sinai Medical Center, Box 1183, One Gustave L. Levy Place, New York, NY 10029 (firstname.lastname@example.org).
Acquisition of data: Rudich, Curcio, Brodie.
Analysis and interpretation of data: All authors.
Drafting of the manuscript: Rudich, Curcio, Brodie.
Critical revision of the manuscript for important intellectual content: All authors.
Study supervision: Brodie.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported in part by an unrestricted grant from Research to Prevent Blindness to the Department of Ophthalmology, Mount Sinai School of Medicine, grant EY06109 from the National Institutes of Health and unrestricted funds from Research to Prevent Blindness and the EyeSight Foundation of Alabama to the Department of Ophthalmology, University of Alabama at Birmingham, and grant 5 MO1 RR00071 from the National Center for Research Resources, National Institutes of Health to the Mount Sinai General Clinical Research Center.
Additional Contributions: The OCT images in Figure 1A were graciously provided by Martin Pearlman, MD, East Lansing, Michigan.