Submitted for Publication: January 2, 2013; final revision received April 27, 2013; accepted May 6, 2013.
Published Online: October 10, 2013. doi:10.1001/jamaophthalmol.2013.5002.
Study concept and design: McLaughlin, Paglione, Slakter, Ye, Xu, Suttle, Kim.
Acquisition of data: McLaughlin, Paglione, Tolentino, Xu.
Analysis and interpretation of data: McLaughlin, Paglione, Slakter, Ye, Xu, Suttle, Kim.
Drafting of the manuscript: McLaughlin, Paglione, Tolentino, Ye, Xu, Suttle, Kim.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Ye.
Obtained funding: McLaughlin.
Administrative, technical, or material support: Paglione, Tolentino.
Study supervision: McLaughlin, Paglione, Xu, Kim.
Conflict of Interest Disclosures: The study was financially supported by GlaxoSmithKline. Mss McLaughlin and Ye and Drs Paglione, Xu, Suttle, and Kim are employees of GlaxoSmithKline.
Role of the Sponsor: The sponsor participated in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We acknowledge the contributions of study participants, investigators ((Nicole Grunenberg, MD, Thomas Hunt, MD, Susanne Swan, MD, Brian B. Berger, MD, Joel Pearlman, MD, Thomas Ciulla, MD, and Louis C. Glazer, MD), and clinical site staff and Mohammad Hossain, PhD, Valeriu Damian-lordache, PhD, Nan Bing, PhD, and Sandy Stinnett, MS, for assistance in design and analysis, and Joanne Parker, BS, of Fishawack Scientific Communications provided writing and editing support funded by GlaxoSmithKline.