Submitted for Publication: January 19, 2013; final revision received April 24, 2013; accepted May 9, 2013.
Published Online: October 17, 2013. doi:10.1001/jamaophthalmol.2013.5018.
Study concept and design: Gill, Moscato, Chang, Silkiss.
Acquisition of data: Gill, Moscato, Chang, Silkiss.
Analysis and interpretation of data: All authors.
Drafting of the manuscript: Gill, Moscato, Chang, Silkiss.
Critical revision of the manuscript for important intellectual content: Moscato, Chang, Soon, Silkiss.
Statistical analysis: Silkiss.
Administrative, technical, or material support: Gill, Moscato, Chang, Silkiss.
Study supervision: Moscato, Silkiss
Conflict of Interest Disclosures: Dr Soon has served on the speakers bureau of Genentech/Roche. No other disclosures were reported.
Funding/Support: Two cases were part of an Expanded Access study sponsored by Genentech (NCT1160250).
Role of the Sponsor: Genentech had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.