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Aspirin Use and Aging Macula Disorder

Paulus T. V. M. de Jong, MD, PhD1,2,3; Jie Jin Wang, MMed, PhD4,5; Astrid E. Fletcher, PhD6
[+] Author Affiliations
1Department of Ophthalmogenetics, Netherlands Institute of Neurosciences, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands
2Department of Ophthalmology, Academic Medical Center, Amsterdam, the Netherlands
3Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands
4Centre for Vision Research, Department of Ophthalmology and the Westmead Millennium Institute, University of Sydney, Sydney, Australia
5Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia
6Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
JAMA Ophthalmol. 2014;132(1):9-10. doi:10.1001/jamaophthalmol.2013.5193.
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For nearly half a century, associations between aspirin use and aging macula disorder (also termed age-related macular degeneration [both AMD]) have been described, predominantly from case reports and small clinical studies. In the last year, the publication of more robust evidence from 3 population-based studies has reawakened interest in this question.13

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