Submitted for Publication: April 1, 2013; final revision received June 23, 2013; accepted June 24, 2013.
Published Online: December 5, 2013. doi:10.1001/jamaophthalmol.2013.6310.
Study concept and design: Gendy.
Acquisition of data: Gendy, Wendel, Pieramici, Miller, Jampol.
Analysis and interpretation of data: Gendy, Fawzi, Pieramici, Jampol.
Drafting of the manuscript: Gendy, Pieramici.
Critical revision of the manuscript for important intellectual content: Fawzi, Wendel, Miller, Jampol.
Obtained funding: Jampol.
Administrative, technical, and material support: Gendy, Wendel.
Study supervision: Fawzi, Jampol.
Conflict of Interest Disclosures: Dr Pieramici has worked as a consultant for Genentech, Alimera, Thrombogenics, Allergan, and Santen. Dr Jampol has worked as a consultant for Baxter International and Stem Cell Organization/Quintiles. No other disclosures were reported.
Funding/Support: This study was supported in part by unrestricted grants from Research to Prevent Blindness (Department of Ophthalmology Northwestern University) and the Macula Foundation (Dr Jampol) and by a gift from Mary Dempsey and Kevin Hitzeman (Dr Jampol).
Role of the Sponsor: The funding agencies had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.