The allergenic role of cocamidopropyl betaine (CAPB) in contact dermatitis, including eyelid dermatitis, is well documented in the dermatology literature. Despite widespread use of this surfactant in many cosmetic and self-care products, including some commonly prescribed by ophthalmologists for eyelid hygiene, we found no mention of this allergen in the ophthalmic literature.
Article InformationCorresponding Author: Andrew J. Hendershot, MD, Havener Eye Institute, The Ohio State University Wexner Medical Center, 915 Olentangy River Rd, Ste 5000, Columbus, OH 43212 (firstname.lastname@example.org).
Published Online: January 9, 2014. doi:10.1001/jamaophthalmol.2013.6254.
Study concept and design: Welling, Mauger, Hendershot.
Acquisition of data: Welling, Mauger, Hendershot.
Analysis and interpretation of data: Welling, Mauger, Schoenfield.
Drafting of the manuscript: Welling, Mauger, Schoenfield.
Critical revision of the manuscript for important intellectual content: Welling, Mauger, Hendershot.
Administrative, technical, or material support: All authors.
Study supervision: Mauger, Hendershot.
Conflict of Interest Disclosures: None reported.