Submitted for Publication: May 15, 2013; final revision received October 25, 2013; accepted November 4, 2013.
Published Online: February 6, 2014. doi:10.1001/jamaophthalmol.2013.7987.
Study concept and design: Greenberg, Yannuzzi, Tsang.
Acquisition of data: Greenberg, Zweifel, Duncker, Kohl, Baumann, Tsang.
Analysis and interpretation of data: Greenberg, Sherman, Chen, Kohl, Baumann, Wissinger, Tsang.
Drafting of the manuscript: Greenberg, Kohl, Baumann, Tsang.
Critical revision of the manuscript for important intellectual content: Sherman, Zweifel, Chen, Duncker, Kohl, Wissinger, Yannuzzi, Tsang.
Statistical analysis: Greenberg, Tsang.
Obtained funding: Wissinger, Yannuzzi, Tsang.
Administrative, technical, or material support: Sherman, Chen, Duncker, Kohl, Baumann.
Study supervision: Zweifel, Wissinger, Yannuzzi, Tsang.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported, in part, by grants EY018213 (Dr Tsang) and RO1-EY02115 (R. Theodore Smith) from the National Eye Institute/National Institutes of Health; P30EY019007 from Core Support for Vision Research, Columbia University; C026448 from New York Stem Cell Science; Foundation Fighting Blindness; the Macula Foundation Inc; TS080017 from the Department of Defense; and unrestricted funds from Research to Prevent Blindness. Dr Tsang is a Burroughs-Wellcome Program in Biomedical Sciences Fellow, and is also supported by the Charles E. Culpeper–Partnership for Cures 07-CS3, Crowley Research Fund, Schneeweiss Stem Cell Fund, New York State grant N09G-302, and a Joel Hoffmann Scholarship.
Role of the Sponsor: None of the sponsors or funding organizations had a role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Janet R. Sparrow, PhD, Department of Ophthalmology, Columbia University, provided helpful comments, and R. Theodore Smith, MD, PhD, Department of Ophthalmology, Columbia University (currently, Department of Ophthalmology, New York University) shared equipment. Neither received compensation for their contributions.