Submitted for Publication: December 18, 2012; final revision received November 20, 2013; accepted December 8, 2013.
Published Online: February 20, 2014. doi:10.1001/jamaophthalmol.2013.8175.
Study concept and design: Caire, Recalde, Fernandez-Robredo, García-Layana.
Acquisition of data: Caire, Recalde, Velazquez-Villoria, Garcia-Garcia.
Analysis and interpretation of data: Caire, Recalde, Velazquez-Villoria, Reiter, Anter, Fernandez-Robredo, García-Layana.
Drafting of the manuscript: Caire, Recalde, Garcia-Garcia, Anter.
Critical revision of the manuscript for important intellectual content: Caire, Recalde, Velazquez-Villoria, Reiter, Fernandez-Robredo, García-Layana.
Statistical analysis: Caire, Recalde, Anter.
Obtained funding: Caire, Recalde, Fernandez-Robredo, García-Layana.
Administrative, technical, and material support: Velazquez-Villoria, Garcia-Garcia, Reiter.
Study supervision: Caire, Recalde, Fernandez-Robredo, García-Layana.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported in part by grants PI08/1705 and Red Temática de Investigación Cooperativa en Salud (RETICS) RD07/0062 from the Ministerio de Ciencia e Innovación and grants PI11/00898 and RETICS RD12/0034 from the Ministerio de Economía y Competitividad. Drs Recalde, Fernandez-Robredo, and García-Layana and Ms Garcia-Garcia are members of RETICS RD07/0062 and RD12/0034.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Group Information: The members of the Spanish Multicenter Group on AMD are Miguel Ángel Zapata, MD, PhD, Hospital Vall d’Hebron, Barcelona, Spain; José María Ruiz-Moreno, MD, PhD, and Carlos Cava, MD, PhD, Universidad Castilla-La Mancha, Albacete, Spain; Rosa Coco, MD, PhD, Instituto de Oftalmolobiología Aplicada, Universidad de Valladolid, Valladolid, Spain; Lluís Arias, MD, PhD, Hospital de Bellvitge, Barcelona, Spain; Clemencia Torrón, MD, PhD, and Oscar Ruiz-Moreno, MD, PhD, Hospital Miguel Servet, Zaragoza, Spain; Henar Heras, MD, PhD, Complejo Hospitalario de Navarra, Pamplona, Spain; María Isabel López-Gálvez, MD, PhD, Hospital Clínico Universitario, Valladolid, Spain; Juan Donate, MD, PhD, Hospital Clínico, Madrid, Spain; Miguel Ángel de la Fuente, MD, PhD, Fundación Jiménez Díaz, Madrid, Spain; Ana María Gómez-Ramírez, MD, PhD, Hospital Reina Sofía, Murcia, Spain; and Rosa Sanabría, MD, PhD, Hospital San Telmo, Palencia, Spain.
Additional Contributions: We express our appreciation to all of the participants and their relatives, who generously participated in the study. Santiago Rodríguez de Cordoba, PhD, Centro de Investigaciones Biológicas, Madrid, Spain, provided helpful comments and corrections on the manuscript, and Vanessa Fernandez García, MS, and Maite Moreno Orduña, BS, Universidad de Navarra, Pamplona, Spain, provided excellent technical assistance; they received no compensation for their contributions.