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Varicella-Zoster Virus Detection in Varicella-Associated Stromal Keratitis

Alice Y. Matoba, MD1; Beeran Meghpara, MD1; Paty Chevez-Barrios, MD2
[+] Author Affiliations
1Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas
2Department of Pathology and Genomic Medicine, Houston Methodist Hospital and Weill Medical College of Cornell University, Houston, Texas
JAMA Ophthalmol. 2014;132(4):505-506. doi:10.1001/jamaophthalmol.2013.8254.
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Stromal keratitis is a well-known development in herpes zoster ophthalmicus but is uncommonly noted following varicella, the primary infection with varicella-zoster virus.1 Keratitis typically occurs several weeks to months following varicella and is often described as disciform in nature. We describe a case of varicella-associated stromal keratitis in which the cornea was positive for varicella-zoster virus by polymerase chain reaction (PCR) testing. We believe that this is the first case of varicella-associated stromal keratitis documented by identification of varicella-zoster virus in the cornea.

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Full-Thickness Corneal Scarring With Intact Epithelium Following Corticosteroid Therapy for Varicella-Associated Stromal Keratitis
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