Submitted for Publication: May 21, 2013; final revision received February 10, 2014; accepted February 15, 2014.
Published Online: June 5, 2014. doi:10.1001/jamaophthalmol.2014.1008.
Study concept and design: Y. Uchino, M. Uchino, Yokoi, Dogru, Kinoshita, Tsubota.
Acquisition, analysis, or interpretation of data: Y. Uchino, M. Uchino, Yokoi, Dogru, Kawashima, Okada, Inaba, Tamaki, Komuro, Sonomura, Kato, Argüeso.
Drafting of the manuscript: Y. Uchino, M. Uchino, Yokoi, Dogru, Inaba, Tamaki.
Critical revision of the manuscript for important intellectual content: Y. Uchino, Dogru, Kawashima, Okada, Komuro, Sonomura, Kato, Argüeso, Kinoshita, Tsubota.
Statistical analysis: Y. Uchino.
Obtained funding: M. Uchino.
Administrative, technical, or material support: Y. Uchino, Yokoi, Okada.
Study supervision: Y. Uchino, M. Uchino, Dogru, Kawashima, Argüeso, Kinoshita, Tsubota.
Conflict of Interest Disclosures: Messrs Inaba and Tamaki are employees of Santen Pharmaceutical Co, Ltd. Drs Kinoshita and Tsubota are consultants for Santen Pharmaceutical Co, Ltd. No other disclosures were reported.
Funding/Support: This study was supported by Grant-in-Aid for Young Scientists (B) 2010, 2279192 from the Ministry of Health, Labour, and Welfare and the Ministry of Education, Science, Sports, and Culture. Provision of facilities, transport of equipment, data analysis, and data management were supported by Santen Pharmaceutical Co, Ltd.
Role of the Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.