Polymerase chain reaction (PCR) to detect Mycobacterium tuberculosis in tubercular uveitis is limited by low sensitivity, expensive equipment, sophisticated laboratory facilities, and expertise. We evaluated loop-mediated isothermal amplification (LAMP) assay1 targeting the IS6110 region of M tuberculosis in intraocular samples from patients with tubercular uveitis.
Article InformationCorresponding Author: Amod Gupta, MD, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India 160012 (firstname.lastname@example.org).
Study concept and design: K. Sharma, A. Sharma, Gupta.
Acquisition, analysis, or interpretation of data: K. Sharma, Bansal, A. Sharma, Beke.
Drafting of the manuscript: K. Sharma, Bansal, A. Sharma, Beke.
Critical revision of the manuscript for important intellectual content: K. Sharma, Gupta.
Statistical analysis: K. Sharma.
Administrative, technical, or material support: A. Sharma, Gupta.
Study supervision: Bansal, Gupta.
Conflict of Interest Disclosures: None reported.