0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Observation |

Diffuse Retinal Ischemia Following Intravenous Crushed Oxymorphone Abuse

Rohan J. Shah, MD1; Edward F. Cherney, MD1
[+] Author Affiliations
1Vanderbilt Eye Institute, Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee
JAMA Ophthalmol. 2014;132(6):780-781. doi:10.1001/jamaophthalmol.2014.324.
Text Size: A A A
Published online

Extract

A unique case of diffuse retinal ischemia following intravenous abuse of crushed extended-release oxymorphone hydrochloride (Opana ER) is reported. This case highlights a potentially blinding condition as a result of retinal vascular endothelial injury following intravenous abuse of a medication intended for oral use.

Article InformationCorresponding Author: Edward F. Cherney, MD, Vanderbilt Eye Institute, 2311 Pierce Ave, Nashville, TN 37232 (edward.cherney@vanderbilt.edu).

Author Contributions: Drs Shah and Cherney had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Shah, Cherney.

Acquisition, analysis, or interpretation of data: Shah, Cherney.

Drafting of the manuscript: Shah.

Critical revision of the manuscript for important intellectual content: Shah, Cherney.

Administrative, technical, or material support: Shah, Cherney.

Study supervision: Cherney.

Conflict of Interest Disclosures: None reported.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure 2.
Spectral-Domain Optical Coherence Tomographic Images and Color Fundus Photographs at Follow-up

Spectral-domain optical coherence tomographic images of the patient’s right (A) and left (B) maculae reveal diffuse inner retinal thinning from ischemia and loss of normal foveal contour. Montage color fundus photographs of the patient’s right (C) and left (D) eyes at the most recent follow-up delineate increased arteriovenous sheathing and ischemia with peripheral panretinal photocoagulation scars.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 1.
Color Fundus Photographs and Fluorescein Angiograms

Montage color fundus photographs demonstrate arteriovenous tortuosity, scattered hemorrhages, and ischemia in the patient’s right eye (A) and arteriovenous tortuosity, disc neovascularization, cotton-wool spots and hemorrhages, and ischemia in the patient’s left eye (B). Montage fluorescein angiograms of the patient’s right (C) and left (D) eyes reveal diffuse retinal ischemia and capillary dropout.

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

238 Views
0 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();