Submitted for Publication: May 24, 2013; final revision received February 19, 2014; accepted February 20, 2014.
Published Online: June 19, 2014. doi:10.1001/jamaophthalmol.2014.1683.
Study concept and design: Mrejen, Jampol, Yannuzzi.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Mrejen, Gallego-Pinazo, Jampol, Yannuzzi.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Mrejen, Yannuzzi.
Obtained funding: Jampol, Yannuzzi.
Administrative, technical, or material support: Khan.
Study supervision: Gallego-Pinazo, Jampol, Yannuzzi.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by The Macula Foundation, by an unrestricted grant from Research to Prevent Blindness (to Northwestern University), and by a gift from Kevin Hitzeman and Mary Dempsey.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Salomon Yves Cohen, MD, PhD (Centre Ophtalmo Imagerie Laser, Paris, France), Sharon Fekrat, MD (Duke University Eye Center, Durham, North Carolina), S. Krishna Mukkamala, MD (Vitreous Retina Macula Consultants of New York, New York, New York), Hermann Schubert, MD (Edward S. Harkness Eye Institute, New York, New York), Jerome Sherman, OD (State University of New York College of Optometry, New York, New York), and Richard F. Spaide, MD (Vitreous Retina Macula Consultants of New York, New York, New York) contributed cases to this study.