Submitted for Publication: February 27, 2014; final revision received April 8, 2014; accepted April 9, 2014.
Published Online: June 26, 2014. doi:10.1001/jamaophthalmol.2014.1604.
Study concept and design: Quinn, Ying, Hildebrand, Ells, Baumritter, Kemper, Wade.
Acquisition, analysis, or interpretation of data: Quinn, Ying, Daniel, Hildebrand, Ells, Baumritter, Schron, Wade.
Drafting of the manuscript: Quinn.
Critical revision of the manuscript for important intellectual content: Ying, Daniel, Hildebrand, Ells, Baumritter, Kemper, Schron, Wade.
Statistical analysis: Quinn, Ying, Kemper, Wade.
Obtained funding: Quinn.
Administrative, technical, or material support: Quinn, Ying, Daniel, Hildebrand, Ells, Baumritter, Schron, Wade.
Study supervision: Quinn, Ying, Daniel, Hildebrand, Baumritter.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Hildebrand reported receiving support from Inoveon Corp and has a patent, Digital Disease Management System, with royalties paid to Inoveon Corp. Dr Ells has received personal fees from the scientific advisory board of Clarity Medical Systems. No other disclosures were reported.
Funding/Support: This study was funded by a cooperative agreement grant (U10 EY017014) from the National Eye Institute of the National Institutes of Health, Department of Health and Human Services. Dr Daniel has received grants from the National Institutes of Health and Dr Hildebrand has received grants from the National Eye Institute; this funding was not related to the current research.
Role of the Sponsor: The study was conducted under a cooperative agreement from the National Eye Institute and, as such, Dr Schron, the National Eye Institute project officer for this study, had input in the collection, management, analysis, and interpretation of the data; preparation, review, and approval of the manuscript; and decision to submit the manuscript for publication, but not the design of the study.
Group Information: The e-ROP Study Group investigators include the following: Office of Study Chair: The Children’s Hospital of Philadelphia: Graham E. Quinn, MD, MSCE (principal investigator [PI]), Kelly Wade, MD, PhD, MSCE, Agnieshka Baumritter, MS, Trang B. Duros, Lisa Erbring; Johns Hopkins University: Michael X. Repka, MD (PI), Jennifer A. Shepard, CRNP, Pamela Donohue, ScD, David Emmert, BA, C. Mark Herring; Boston Children’s Hospital: Deborah VanderVeen, MD, Suzanne Johnston, MD, Carolyn Wu, MD, Jason Mantagos, MD, Danielle Ledoux, MD, Tamar Winter, RN, BSN, IBCLC, Frank Weng, Theresa Mansfield; Nationwide Children’s Hospital and Ohio State University Hospital: Don L. Bremer, MD (PI), Richard Golden, MD, Mary Lou McGregor, MD, Catherine Olson Jordan, MD, David L. Rogers, MD, Rae R. Fellows, MEd, CCRC, Suzanne Brandt, RNC, BSN, Brenda Mann, RNC, BSN; Duke University: David Wallace, MD (PI), Sharon Freedman, MD, Sarah K. Jones, Du Tran-Viet, Rhonda “Michelle” Young; University of Louisville: Charles C. Barr, MD (PI), Rahul Bhola, MD, Craig Douglas, MD, Peggy Fishman, MD, Michelle Bottorff, Brandi Hubbuch, RN, MSN, NNP-BC, Rachel Keith, PhD; University of Minnesota: Erick D. Bothun, MD (PI), Inge DeBecker, MD, Jill Anderson, MD, Ann Marie Holleschau, BA, CCRP, Nichole E. Miller, MA, RN, NNP, Darla N. Nyquist, MA, RN, NNP; University of Oklahoma: R. Michael Siatkowski, MD (PI), Lucas Trigler, MD, Marilyn Escobedo, MD, Karen Corff, MS, ARNP, NNP-BC, Michelle Huynh-Blunt, MS, ARNP, Kelli Satnes, MS, ARNP, NNP-BC; Children’s Hospital of Philadelphia: Monte D. Mills, MD, Will Anninger, MD, Gil Binenbaum, MD, MSCE, Graham E. Quinn, MD, MSCE, Karen A. Karp, BSN, Denise Pearson, COMT; University of Texas Health Science Center at San Antonio: Alice Gong, MD (PI), John Stokes, MD, Clio Armitage Harper, MD, Laurie Weaver, Carmen McHenry, BSN, Kathryn Conner, Rosalind Heemer, Elnora Cokley, RNC, Robin Tragus, MSN, RN, CCRC; University of Utah: Robert Hoffman, MD (PI), David Dries, MD, Katie Jo Farnsworth, Deborah Harrison, MS, Bonnie Carlstrom, Cyrie Ann Frye, CRA, OCT-C; Vanderbilt University: David Morrison, MD (PI), Sean Donahue, MD, Nancy Benegas, MD, Sandy Owings, COA, CCRP, Sandra Phillips, COT, CRI, Scott Ruark; Hospital of the Foothills Medical Center: Anna Ells, MD, FRCS (PI), Patrick Mitchell, MD, April Ingram, Rosie Sorbie, RN. Data Coordinating Center: University of Pennsylvania Perelman School of Medicine: Gui-shuang Ying, PhD (PI), Maureen Maguire, PhD, Mary Brightwell-Arnold, BA, SCP, Max Pistilli, MS, Kathleen McWilliams, CCRP, Sandra Harris, Claressa Whearry; Image Reading Center: University of Pennsylvania Perelman School of Medicine: Ebenezer Daniel, MBBS, MS, MPH (PI), E. Revell Martin, BA, Candace R. Parker Ostroff, Krista Sepielli, Eli Smith. Expert Readers: Antonio Capone, MD, The Vision Research Foundation; G. Baker Hubbard, MD, Emory University School of Medicine; Anna Ells, MD, FRCS, University of Calgary Medical Center. Image Data Management Center: University of Oklahoma Health Sciences Center/Inoveon Corp: P. Lloyd Hildebrand, MD (PI), Kerry Davis, G. Carl Gibson, Regina Hansen. Cost-Effectiveness Component: Alex R. Kemper, MD, MPH, MS (PI), Lisa Prosser, PhD. Data Management and Oversight Committee (DMOC): David C. Musch, PhD, MPH (chair), Stephen P. Christiansen, MD, Ditte J. Hess, CRA, Steven M. Kymes, PhD, SriniVas R. Sadda, MD, Ryan Spaulding, PhD. National Eye Institute: Eleanor B. Schron, PhD, RN.
Additional Contributions: We would like to acknowledge gratefully the contributions of Clare Gilbert, FRCOphth, MD, MSc (London School of Hygiene and Tropical Medicine); Alistair Fielder, FRCOphth (professor emeritus at City University London); and Judith Alexander, BA (former director of the Fundus Photograph Reading Center, Scheie Eye Institute, University of Pennsylvania Perelman School of Medicine), for their contributions to the early development of the e-ROP Study. They did not receive compensation from a funding sponsor for their contributions.