Submitted for Publication: November 20, 2013; final revision received April 4, 2014; accepted April 8, 2014.
Published Online: July 3, 2014. doi:10.1001/jamaophthalmol.2014.1726.
Study concept and design: Sandberg, Pearce, Berson.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Sandberg, Harper, Berson.
Critical revision of the manuscript for important intellectual content: Sandberg, Pearce, Weigel-DiFranco, Hart, Rosner, Berson.
Statistical analysis: Sandberg, Rosner.
Obtained funding: Sandberg, Berson.
Administrative, technical, or material support: Sandberg, Harper, Weigel-DiFranco.
Study supervision: Sandberg, Berson.
Conflict of Interest Disclosures: Dr Pearce was an expert witness for DuPont regarding development of hypothyroidism after exposure to radioactive iodine from the Hanford Nuclear Reservation and is a consultant to Health Canada regarding thyroidal effects of drinking water nitrate concentrations. No other disclosures were reported.
Funding/Support: This study was supported by grant EY019767 from the National Eye Institute; by the Massachusetts Lions Eye Research Fund, Inc; and by a Center Grant from the Foundation Fighting Blindness.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.