We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Observation |

Subretinal Thelazia-Induced Diffuse Unilateral Subacute Neuroretinitis

Paradee Kunavisarut, MD1; Direk Patikulsila, MD1; Pradya Somboon, PhD2; Kessara Pathanapitoon, MD, PhD1; Aniki Rothova, MD, PhD3
[+] Author Affiliations
1Department of Ophthalmology, Chiang Mai University, Chiang Mai, Thailand
2Department of Parasitology, Chiang Mai University, Chiang Mai, Thailand
3Department of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands
JAMA Ophthalmol. 2014;132(7):896-898. doi:10.1001/jamaophthalmol.2014.346.
Text Size: A A A
Published online


Diffuse unilateral subacute neuroretinitis (DUSN) is a parasitic eye infection with characteristic abnormalities of the outer retina and retinal pigment epithelium and is caused by nematode infection, which can be located in the subretinal space.1 It is a primarily unilateral ocular disorder clinically characterized by a decrease in vision associated with vitritis, papillitis, and recurrent development of white linear lesions in the retina. The gold standard of the diagnosis of DUSN is the visualization of a motile worm. Herein, we report a case of subretinal Thelazia-induced DUSN.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Figure 1.
Fundus Photographs and Fluorescein Angiograms of the Right Eye Taken 1 Week After Initial Presentation Demonstrated Diffuse Unilateral Subacute Neuroretinitis

A and B, Fundus photographs showed mild vitritis, vascular sheathing, and diverse chorioretinal lesions. B, In the superior part of the retina, a threadlike lesion (arrowhead) beneath the retina was observed. C and D, Fundus fluorescein angiograms demonstrated multiple diffuse curvilinear lesions characterized by leakage in the late frames.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.
An Adult Thelazia in the Subretinal Space Was Discovered 4 Weeks After Initial Presentation

A, Optical coherence tomography revealed a threadlike parasite located in the subretinal space (arrowheads). B, Fundus photograph taken 1 day after optical coherence tomography revealed that the parasite migrated slightly (arrowhead). C, A female Thelazia 6.25 mm long and 0.1 mm wide (measured at the vulva opening area) was extracted from the subretinal space.

Graphic Jump Location




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.



Thelazia Removal

Removal of the parasite with an extrusion tube during pars plana vitrectomy.

Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Multimedia


Articles Related By Topic
Related Collections
PubMed Articles