Uveal metastasis is often managed by external beam radiation therapy requiring multiple treatment sessions for the patient. We report the first case, to our knowledge, of regression of choroidal metastasis from breast carcinoma after 1 treatment with Leksell Gamma Knife (GK) stereotactic radiosurgery.
Article InformationCorresponding Author: Andre J. Witkin, MD, New England Eye Center, Tufts Medical Center, 800 Washington St, PO Box 450, Boston, MA 02111 (firstname.lastname@example.org).
Published Online: July 17, 2014. doi:10.1001/jamaophthalmol.2014.1974.
Study concept and design: Lally, Duker, Witkin.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Lally, Witkin.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Lally.
Obtained funding: Duker, Witkin.
Administrative, technical, or material support: Lally, Duker, Mignano, Witkin.
Study supervision: Duker, Witkin.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported in part by an unrestricted grant to the New England Eye Center, Tufts University School of Medicine from Research to Prevent Blindness.
Role of the Sponsor: Research to Prevent Blindness was involved in the design and conduct of the study but had no role in the collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.