0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Observation |

Regression of Choroidal Metastasis From Breast Carcinoma Treated With Gamma Knife Radiosurgery ONLINE FIRST

David R. Lally, MD1; Jay S. Duker, MD1; John E. Mignano, MD, PhD2; Stephen Martin, MD3; Andre J. Witkin, MD1
[+] Author Affiliations
1New England Eye Center, Tufts Medical Center, Boston, Massachusetts
2Department of Radiation Oncology, Tufts Medical Center, Boston, Massachusetts
3Department of Ophthalmology, The Aroostook Medical Center, Presque Isle, Maine
JAMA Ophthalmol. Published online July 17, 2014. doi:10.1001/jamaophthalmol.2014.1974
Text Size: A A A
Published online

Extract

Uveal metastasis is often managed by external beam radiation therapy requiring multiple treatment sessions for the patient. We report the first case, to our knowledge, of regression of choroidal metastasis from breast carcinoma after 1 treatment with Leksell Gamma Knife (GK) stereotactic radiosurgery.

Article InformationCorresponding Author: Andre J. Witkin, MD, New England Eye Center, Tufts Medical Center, 800 Washington St, PO Box 450, Boston, MA 02111 (ajwitkin@gmail.com).

Published Online: July 17, 2014. doi:10.1001/jamaophthalmol.2014.1974.

Author Contributions: Dr Witkin had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: Lally, Duker, Witkin.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Lally, Witkin.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Lally.

Obtained funding: Duker, Witkin.

Administrative, technical, or material support: Lally, Duker, Mignano, Witkin.

Study supervision: Duker, Witkin.

Conflict of Interest Disclosures: None reported.

Funding/Support: This work was supported in part by an unrestricted grant to the New England Eye Center, Tufts University School of Medicine from Research to Prevent Blindness.

Role of the Sponsor: Research to Prevent Blindness was involved in the design and conduct of the study but had no role in the collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Figures in this Article

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure 1.
Color Fundus Photograph Montage of the Left Eye Shows a Juxtapapillary 12 × 15-mm Amelanotic Choroidal Mass With Overlying Subretinal Fluid

Retinal pigment epithelial changes are seen along the inferior border of the lesion.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.
Color Fundus Photograph Montage of the Left Eye 1 Year After Treatment With Gamma Knife Radiosurgery

A flat chorioretinal scar with retinal pigment epithelial loss is observed. Two cotton-wool spots (arrowheads) are now evident in the macula at the border of the region of prior radiation treatment.

Graphic Jump Location

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
JAMAevidence.com
brightcove.createExperiences();