Submitted for Publication: December 2, 2013; final revision received April 1, 2014; accepted April 24, 2014.
Published Online: July 24, 2014. doi:10.1001/jamaophthalmol.2014.2333.
Study concept and design: Thulliez, Bejan-Angoulvant.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Thulliez, Angoulvant, Bejan-Angoulvant.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Thulliez, Bejan-Angoulvant.
Administrative, technical, or material support: Jonville-Bera.
Study supervision: Angoulvant, Pisella, Gueyffier, Bejan-Angoulvant.
Conflict of Interest Disclosures: Dr Angoulvant receives personal fees from AstraZeneca, Novartis, Lilly, MSD, Servier Laboratories, Amgen, and Bayer; grants from Lilly; and nonfinancial support from MSD; no funds were received for the present study. Dr Gueyffier receives nonfinancial support from Servier Laboratories; grants from Teva, Bristol-Myers Squibb, Lilly, Janssen-Cilag, UCB Pharma, Novartis, Urgo Pharmaceutical, Schering-Plough, Novo Nordisk, Trophos, and Teikoku Pharma; and has Novadiscovery shares; no funds were received for the present study. No other disclosures are reported.
Additional Contributions: Clémence Bourgeois, BSc (Pharmacology Department, Centre Hospitalier Regional Universitaire de Tours) assisted with review of some of the selected publications. Gilles Paintaud, MD, PhD, and Hervé Watier, MD, PhD, (MabImprove Labex) provided support and advice. There was no financial compensation for the services.