Submitted for Publication: March 25, 2014; final revision received May 25, 2014; accepted July 14, 2014.
Published Online: September 4, 2014. doi:10.1001/jamaophthalmol.2014.3326.
Study concept and design: Pasquale, Jiwani, Rhee, Levkovitch-Verbin.
Acquisition, analysis, or interpretation of data: Jiwani, Zehavi-Dorin, Majd, Rhee, T. Chen, Turalba, Shen, Brauner, Grosskreutz, Gardiner, S. Chen, Borboli-Gerogiannis, Greenstein, Chang, Ritch, Loomis, Kang, Wiggs, Levkovitch-Verbin.
Drafting of the manuscript: Pasquale, Majd, Kang.
Critical revision of the manuscript for important intellectual content: Pasquale, Jiwani, Zehavi-Dorin, Rhee, T. Chen, Turalba, Shen, Brauner, Grosskreutz, Gardiner, S. Chen, Borboli-Gerogiannis, Greenstein, Chang, Ritch, Loomis, Wiggs, Levkovitch-Verbin.
Statistical analysis: Jiwani, Majd, Loomis, Kang.
Obtained funding: Pasquale, Jiwani, Wiggs.
Administrative, technical, or material support: Pasquale, T. Chen, Turalba, Shen, Grosskreutz, Levkovitch-Verbin.
Study supervision: Pasquale, Rhee, Gardiner, Levkovitch-Verbin.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Ritch has received personal fees from iSonic Medical, Sensimed, Aeon Astron, Taejoon Pharmaceutical, Pfizer, Merck, Allergan, and Ocular Instruments Inc outside this work. Dr Wiggs has served on the scientific advisory boards for the Glaucoma Research Foundation and Research to Prevent Blindness. No other disclosures were reported.
Funding/Support: This work was supported by the Arthur Ashley Foundation, grant EY020928 from the National Institutes of Health (Dr Wiggs), a Physician Scientist Award from Research to Prevent Blindness (Dr Pasquale), a Harvard Medical School Ophthalmology Scholar Award (Dr Pasquale), and a Doris Duke Charitable Foundation grant (Dr Jiwani). Dr Wiggs has received an honorarium for travel expenses from Research to Prevent Blindness.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.