Submitted for Publication: May 20, 2014; final revision received July 31, 2014; accepted August 3, 2014.
Published Online: September 25, 2014. doi:10.1001/jamaophthalmol.2014.3602.
Study concept and design: Webers, Nuijts.
Acquisition, analysis, or interpretation of data: Visser, Beckers, Bauer, Gast, Zijlmans, Berenschot, Nuijts.
Drafting of the manuscript: Visser, Nuijts.
Critical revision of the manuscript for important intellectual content: Beckers, Bauer, Gast, Zijlmans, Berenschot, Webers, Nuijts.
Statistical analysis: Visser, Berenschot.
Obtained funding: Nuijts.
Administrative, technical, or material support: Zijlmans, Webers, Nuijts.
Study supervision: Beckers, Bauer, Gast, Nuijts.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Visser reports grants from the Dutch ministry of Health, Welfare and Sport and The Netherlands Organisation for Scientific Research, as well as nonfinancial support from Alcon, during the conduct of the study. Dr Beckers is a consultant for Alcon, MSD, and Pfizer and has received lecture fees from Alcon, MSD, and Pfizer. Dr Bauer received study grants from Alcon, Carl Zeiss, and Physiol and lecture fees from Alcon and MSMS. Dr Gast received grants from ZonMW and nonfinancial support from Alcon during the conduct of the study. Dr Berenschot received nonfinancial support from Alcon during the conduct of the study. Dr Webers is a consultant for Alcon, Allergan, and MSD and has received lecture fees from Alcon, Allergan, and MSD. Dr Nuijts is a consultant for Alcon, Asico, and TheaPharma; has received study grants from Acufocus, Alcon, Carl Zeiss, Ophtec, and Physiol; and has received a lecture fee from Alcon. No other disclosures are reported.
Funding/Support: This study was conducted using ZonMW research grant 171001011, which was provided by the Ministry of Health, Welfare, and Sport and The Netherlands Organisation for Scientific Research.
Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.