0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Reperfusion of Areas of Ischemia in Central Retinal Vein Occlusion—Reply

Motohiro Kamei, MD, PhD1; Kohji Nishida, MD, PhD1
[+] Author Affiliations
1Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan
JAMA Ophthalmol. 2015;133(2):228-229. doi:10.1001/jamaophthalmol.2014.4249.
Text Size: A A A
Published online

Extract

In Reply The summary by Tan and colleagues that the extent of capillary nonperfusion may not be static in ischemic CRVO complements the findings of our study.1

Tan and colleagues pointed out that some studies have reported decreases in areas of nonperfusion in some patients with retinal vein occlusion.2,3 We agree that the study by Campochiaro et al2 mentioned that reperfusion of areas of RNP occurred at a 6- to 8-fold higher rate (6% or 8%) in patients treated with anti-VEGF drugs compared with patients who received sham treatment (1%), which is consistent with our finding that reperfusion of ischemic areas can occur in patients with CRVO after treatment. However, there seem to be slight differences of opinion. The difference between our study and the study by Campochiaro and colleagues is an area of reperfusion; we found reperfusion of large ischemic areas in severe ischemic cases of CRVO, while very few patients with the ischemic type of CRVO were included in their study. The number of patients with more than 5 or 10 DAs of RNP (0-3 patients) did not change significantly over 12 months in their study. Furthermore, most patients with CRVO (about 80%) had no baseline RNP and 12.3% had between 0 and 1 DA of RNP. Therefore, in their study, if reperfusion developed, it was limited to a very small area (perhaps <1 DA).

Topics

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

February 1, 2015
Colin S. Tan, FRCSEd(Ophth); Milton C. Chew, MBBS; SriniVas R. Sadda, MD
1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
2Doheny Eye Institute, University of Southern California, Los Angeles
JAMA Ophthalmol. 2015;133(2):227-228. doi:10.1001/jamaophthalmol.2014.4245.
CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

278 Views
1 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Jobs
brightcove.createExperiences();