Submitted for Publication: July 3, 2014; final revision received September 29, 2014; accepted October 2, 2014.
Published Online: November 20, 2014. doi:10.1001/jamaophthalmol.2014.4755.
Study concept and design: Riemens, Bromberg, Baarsma, Cordero-Coma, Wensing, Lokhorst.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Riemens, Bromberg, Willermain, Erckens.
Critical revision of the manuscript for important intellectual content: Bromberg, Touitou, Sobolewska, Missotten, Baarsma, Hoyng, Cordero-Coma, Tomkins-Netzer, Rozalski, Tugal-Tutkun, Guex-Crosier, Los, Bollemeijer, Nolan, Pawade, Bodaghi, ten Dam-van Loon, Dick, Zierhut, Lightman, Mackensen, Moulin, Wensing, le Hoang, Lokhorst.
Statistical analysis: Riemens, Tomkins-Netzer.
Obtained funding: Riemens.
Administrative, technical, or material support: Touitou, Sobolewska, Baarsma, Cordero-Coma, Bollemeijer, Pawade, ten Dam-van Loon, Dick, Erckens, Wensing.
Study supervision: Missotten, Hoyng, Guex-Crosier, Moulin, Lokhorst.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: Funding was provided by Dr PF Fischer Stichting, Landelijke stichting voor Blinden en Slechtzienden, Stichting Nederlands Oogheelkundig Onderzoek, Stichting Blindenpenning, Gelderse Blinden Stichting, the Netherlands.
Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Alfredo Adán, MD, PhD (Hospital Clinic, Barcelona, Spain), Carme Maciá, MD (Hospital Vall D´Hebrón, Barcelona, Spain), Manuel Díaz-Llopis, MD, PhD (Hospital La Fe, Valencia, Spain), and José Luis Olea, MD, PhD (Hospital Son Espases, Mallorca, Spain), contributed data on the Spanish cohort of patients of this study. They did not receive financial compensation.