Submitted for Publication: August 5, 2014; final revision received September 23, 2014; accepted September 27, 2014.
Published Online: November 20, 2014. doi:10.1001/jamaophthalmol.2014.4766.
Study concept and design: Jirawison, Leenasirimakul, Chen, Patikulsila, Ausayakhun, Heiden, Margolis, Keenan.
Acquisition, analysis, or interpretation of data: Jirawison, Yen, Leenasirimakul, Chen, Guadanant, Kunavisarut, Watanachai, Holland.
Drafting of the manuscript: Yen, Guadanant, Kunavisarut, Watanachai, Keenan.
Critical revision of the manuscript for important intellectual content: Jirawison, Yen, Leenasirimakul, Chen, Patikulsila, Ausayakhun, Heiden, Holland, Margolis.
Statistical analysis: Yen, Keenan.
Obtained funding: Margolis.
Administrative, technical, or material support: Jirawison, Leenasirimakul, Chen, Guadanant, Kunavisarut, Patikulsila, Watanachai, Ausayakhun, Heiden, Holland, Margolis.
Study supervision: Jirawison, Leenasirimakul, Margolis.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Holland has served on advisory boards for the following companies: Genentech, Inc, Novartis International AG, Santen, Inc, and Xoma (US) LLC. Dr Margolis has pending intellectual property with the University of California, San Francisco, describing a mobile phone camera for retinal imaging, which at the current time has no financial value. No other disclosures were reported.
Funding/Support: This study was supported by the Gladstone Institute of Virology and Immunology Center for AIDS Research and the Research Evaluation and Allocation Committee, University of California, San Francisco; by grant K23EY019071 from the National Eye Institute; and by That Man May See, the Littlefield Trust, the Peierls Foundation, and the Doris Duke Charitable Foundation through a grant supporting the Doris Duke International Clinical Research Program at the University of California, San Francisco. Mr Yen is a Doris Duke International Clinical Research Fellow.
Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.