Submitted for Publication: September 3, 2014; final revision received October 17, 2014; accepted October 22, 2014.
Published Online: December 11, 2014. doi:10.1001/jamaophthalmol.2014.5108.
Study concept and design: B. E. K. Klein.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: B. E. K. Klein.
Critical revision of the manuscript for important intellectual content: Myers,Howard, R. Klein.
Statistical analysis: Myers, Howard.
Obtained funding: B. E. K. Klein, R. Klein.
Study supervision: B. E. K. Klein, R. Klein.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: This research was supported by grant EY016379 from the National Institutes of Health (Drs R. Klein and B. E. K. Klein) and an unrestricted grant from Research to Prevent Blindness, New York, New York.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The content is solely the responsibility of the authors and does not necessarily reflect the official views of the National Eye Institute or the National Institutes of Health.
Previous Presentation: An abstract of this study was presented at the 2014 Annual Meeting of the Association for Research and Vision in Ophthalmology (ARVO); May 7, 2014; Orlando, Florida.