0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
In This Issue of JAMA Ophthalmology |

Highlights FREE

JAMA Ophthalmol. 2015;133(2):119. doi:10.1001/jamaophthalmol.2014.3702.
Text Size: A A A
Published online

RESEARCH

To investigate the effect of the severity of age-related macular degeneration (AMD) in 1 eye on the incidence, progression, and regression of AMD in the fellow eye, Gangnon and colleagues evaluate retinal photographs and adjust for age, sex, the Y402H polymorphism in the complement factor H gene on chromosome 1q, and mortality. The authors estimated that approximately 50% of participants who developed any AMD always maintained AMD severity states within 1 step of each other between eyes while 90% of participants stayed within 2 steps. Understanding the course of AMD and the risk for earlier stages of AMD worsening based on either the worse or better eye may help in determining how often patients who are at risk for worsening of AMD should be seen.

This retrospective international cooperative study involving 6 eye cancer centers during 30 years identified 106 patients with ocular adnexal diffuse large B-cell lymphoma followed up for a median of 52 months. Munch-Petersen and colleagues report the 5-year overall survival among the entire cohort as 36% (median, 3.5 years; 95% CI, 2.5-4.5 years), with a relapse in 44%. Increasing T category of the TNM staging system (based on the size and/or extent of the primary tumor [T] and whether cancer cells have spread to nearby [regional] lymph nodes [N] and whether metastasis [M], or the spread of the cancer to other parts of the body, have occurred) was predictive of disease-specific survival (P = .04).

Owsley and colleagues examine the rate and types of diabetic retinopathy (DR) identified through a telemedicine screening program using a nonmydriatic camera, as well as the rate of other ocular findings at 4 urban clinic or pharmacy settings in the United States serving predominantly ethnic/racial minority and uninsured persons with diabetes mellitus. Among 1894 persons screened, 21.7% had DR in at least 1 eye. The most common type of DR (94.1%) was mild or moderate nonproliferative DR. In addition, 44.2% of the sample screened had ocular findings other than DR, among which 30.7% were cataract. A collateral benefit of such DR screening programs that may be underappreciated is the detection of other ocular conditions.

Continuing Medical Education and Journal Club

Narayanaswamy and colleagues randomly assign 100 patients with primary angle closure (PAC) or PAC glaucoma to selective laser trabeculopalsty (SLT), repeated if the intraocular pressure (IOP) reduction was less than 20% from baseline at the 1- or 3-month follow-up visit, or to travoprost. They could not identify differences between the SLT and travoprost groups in the absolute mean reduction of IOP (4.0 vs 4.2 mm Hg, respectively; P = .78) or in the percentage of reduction in IOP (16.9% vs 18.5%, respectively; P = .52) at 6 months, although complete success (IOP ≤ 21 mm Hg without medications) was achieved in 60.0% eyes of the SLT group compared with 84.0% of eyes in the travoprost group (P = .008). The authors concluded that while eyes with PAC or PAC glaucoma respond to SLT in the short term, the overall long-term therapeutic effectiveness needs further evaluation.

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

594 Views
0 Citations
×

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs