Submitted for Publication: October 15, 2014; final revision received January 16, 2015; accepted January 29, 2015.
Published Online: March 26, 2015. doi:10.1001/jamaophthalmol.2015.0460.
Study concept and design: Daniel, Quinn, Ying.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Daniel, Quinn, Hubbard.
Critical revision of the manuscript for important intellectual content: Daniel, Quinn, Hildebrand, Ells, Capone, Martin, Ostroff, Smith, Pistilli, Ying.
Statistical analysis: Daniel, Quinn, Pistilli, Ying.
Obtained funding: Quinn.
Administrative, technical, or material support: Daniel, Hildebrand, Ells, Martin, Ostroff, Smith.
Study supervision: Daniel, Quinn, Hildebrand, Ying.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Hildebrand reported receiving consulting fees from Inoveon Corp, serving as chairman of the board of directors for Inoveon Corp, and receiving royalties for US patents 5940802 and 6470320, “Digital Disease Management System” (assignee: Board of Regents, University of Oklahoma). Dr Ells reported serving as a member of the scientific advisory board for Clarity Systems. Dr Hubbard reported receiving payment from the University of Pennsylvania as an expert grader of photographs in this work and receiving consulting fees from VisionQuest Biomedical, LLC for grading photographs outside this work. Dr Capone reported being a founding partner of FocusROP, LLC. Dr Ying reported serving as a statistical consultant for Janssen Research and Development, LLC. No other disclosures were reported.
Funding/Support: This work was supported by cooperative agreement grant U10 EY017014 from the National Eye Institute.
Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Group Information: Members of the e-ROP Cooperative Group include the following: Office of Study Chair, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania: Graham E. Quinn, MD, MSCE (principal investigator [PI]), Kelly C. Wade, MD, PhD, MSCE, Agnieshka Baumritter, MS, Trang B. Duros, and Lisa Erbring; Johns Hopkins University, Baltimore, Maryland: Michael X. Repka, MD (PI), Jennifer A. Shepard, CRNP, David Emmert, BA, and C. Mark Herring; Boston Children’s Hospital, Boston, Massachusetts: Deborah VanderVeen, MD (PI), Suzanne Johnston, MD, Carolyn Wu, MD, Jason Mantagos, MD, Danielle Ledoux, MD, Tamar Winter, RN, BSN, IBCLC, Frank Weng, and Theresa Mansfield, RN; Nationwide Children’s Hospital and Ohio State University Hospital, Columbus: Don L. Bremer, MD (PI), Mary Lou McGregor, MD, Catherine Olson Jordan, MD, David L. Rogers, MD, Rae R. Fellows, MEd, CCRC, Suzanne Brandt, RNC, BSN, and Brenda Mann, RNC, BSN; Duke University, Durham, North Carolina: David Wallace, MD (PI), Sharon Freedman, MD, Sarah K. Jones, Du Tran-Viet, and Rhonda “Michelle” Young; University of Louisville, Louisville, Kentucky: Charles C. Barr, MD (PI), Rahul Bhola, MD, Craig Douglas, MD, Peggy Fishman, MD, Michelle Bottorff, Brandi Hubbuch, RN, MSN, NNP-BC, and Rachel Keith, PhD; University of Minnesota, Minneapolis: Erick D. Bothun, MD (PI), Inge DeBecker, MD, Jill Anderson, MD, Ann Marie Holleschau, BA, CCRP, Nichole E. Miller, MA, RN, NNP, and Darla N. Nyquist, MA, RN, NNP; University of Oklahoma, Oklahoma City: R. Michael Siatkowski, MD (PI), Lucas Trigler, MD, Marilyn Escobedo, MD, Karen Corff, MS, ARNP, NNP-BC, Michelle Huynh, MS, ARNP, and Kelli Satnes, MS, ARNP, NNP-BC; The Children’s Hospital of Philadelphia: Monte D. Mills, MD (PI), Will Anninger, MD, Gil Binenbaum, MD, MSCE, Graham E. Quinn, MD, MSCE, Karen A. Karp, BSN, and Denise Pearson, COMT; University of Texas Health Science Center, San Antonio: Alice Gong, MD (PI), John Stokes, MD, Clio Armitage Harper, MD, Laurie Weaver, Carmen McHenry, BSN, Kathryn Conner, Rosalind Heemer, and Elnora Cokley, RNC; University of Utah, Salt Lake City: Robert Hoffman, MD (PI), David Dries, MD, Katie Jo Farnsworth, Deborah Harrison, MS, Bonnie Carlstrom, and Cyrie Ann Frye, CRA, OCT-C; Vanderbilt University, Nashville, Tennessee: David Morrison, MD (PI), Sean Donahue, MD, Nancy Benegas, MD, Sandy Owings, COA, CCRP, Sandra Phillips, COT, CRI, and Scott Ruark; Hospital of the Foothills Medical Center, Calgary, Alberta, Canada: Anna Ells, MD, FRCS(C) (PI), Patrick Mitchell, MD, April Ingram, and Rosie Sorbie, RN; Data Coordinating Center, University of Pennsylvania School of Medicine, Philadelphia: Gui-Shuang Ying, PhD (PI), Maureen Maguire, PhD, Mary Brightwell-Arnold, BA, SCP, Maxwell Pistilli, MS, Kathleen McWilliams, CCRP, Sandra Harris, and Claressa Whearry; Image Reading Center, University of Pennsylvania School of Medicine, Philadelphia: Ebenezer Daniel, MBBS, MS, MPH, PhD (PI), E. Revell Martin, BA, Candace P. Ostroff, BA, Krista Sepielli, and Eli Smith, BA; Expert Readers: Antonio Capone Jr, MD (The Vision Research Foundation, Royal Oak, Michigan), G. Baker Hubbard III, MD (Emory University School of Medicine, Atlanta, Georgia), and Anna Ells, MD, FRCS(C) (University of Calgary Medical Center, Calgary); Image Data Management Center, Inoveon Corp, Oklahoma City: P. Lloyd Hildebrand, MD (PI), Kerry Davis, G. Carl Gibson, and Regina Hansen; Cost-Effectiveness Component: Alex R. Kemper, MD, MPH, MS (PI), and Lisa Prosser, PhD; Data Management and Oversight Committee: David C. Musch, PhD, MPH (chair), Stephen P. Christiansen, MD, Ditte J. Hess, CRA, Steven M. Kymes, PhD, SriniVas R. Sadda, MD, and Ryan Spaulding, PhD; and National Eye Institute, Bethesda, Maryland: Eleanor B. Schron, PhD, RN.