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Eyes on Ebola Virus Disease

Christine Shieh, MD1; Gargi Vora, MD1; Terry Kim, MD1
[+] Author Affiliations
1Department of Ophthalmology, Duke University, Durham, North Carolina
JAMA Ophthalmol. 2015;133(7):743-744. doi:10.1001/jamaophthalmol.2015.0703.
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This Viewpoint reports on Ebola virus disease and the current Ebola epidemic, which has been deemed the largest in history.

The current Ebola epidemic has been deemed the largest in history, with the World Health Organization declaring it a “public health emergency of international concern.”1 Ebola virus disease has a high fatality rate, and the Ebola virus belongs to the family Filoviridae, a family of viruses that causes hemorrhagic fever in humans and nonhuman primates.2 Bats are suspected to be the reservoir hosts.2

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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Eyes on Ebola: Permanent eye tissue donor deferral
Posted on July 13, 2015
David B. Glasser, M.D.
Johns Hopkins University Department of Ophthalmology
Conflict of Interest: None Declared
I read Dr. Shieh and co-authors recent viewpoint on Ebola virus and the eye with interest. They provide a concise and useful review.

Since the time of preparation of Shieh's manuscript, Varkey and co-authors have published a report of Ebola virus persisting in the aqueous humor of an infected individual up to 14 weeks after the onset of the disease and up to 9 weeks after clearance of the viremia. (Varkey JB, Shantha JG, Crozier I, et al. Persistence of Ebola virus in ocular fluid during convalescence. N Engl J Med. 2015 Jun 18;372(25):2423-7). It is unclear how long infectious virus might persist in ocular tissues after recovery from the disease.

In response to this report, the Eye Bank Association of America's (EBAA) Medical Advisory Board changed the EBAA Medical Standards to permanently exclude from donation all individuals with a history of Ebola virus disease.
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