We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Contemplating the Diagnostic Certainty of Primary Iris Mucosa-Associated Lymphoid Tissue Lymphoma—Reply

Hakan Demirci, MD1; Victor M. Elner, MD, PhD1
[+] Author Affiliations
1Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor
JAMA Ophthalmol. 2015;133(8):970. doi:10.1001/jamaophthalmol.2015.1167.
Text Size: A A A
Published online


In Reply We thank Dr Margo for his comments concerning methods used to diagnose MALT lymphoma. The diagnosis of these lymphomas is usually made on the basis of morphology supported by immunohistochemical and flow cytometric studies. Polymerase chain reaction is rarely necessary. However, ophthalmic pathology biopsy specimens—particularly those of intraocular, optic nerve, or posterior orbital origin—may contain scant material, precluding flow cytometry. In such cases, the diagnosis is based on morphology and a limited number of immunohistochemical stains. The FNA biopsy performed in this case had the disadvantage of very limited available tissue, placing a premium on cytopathologic examination and a few immunohistochemical stains.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





August 1, 2015
Curtis E. Margo, MD, MPH
1Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa2Department of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa
JAMA Ophthalmol. 2015;133(8):969-970. doi:10.1001/jamaophthalmol.2015.1153.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...