Submitted for Publication: January 8, 2015; final revision received March 17, 2015; accepted March 19, 2015.
Published Online: May 21, 2015. doi:10.1001/jamaophthalmol.2015.1320.
Study concept and design: Bonini Filho, Ferrara, Adhi, Witkin, Duker, Waheed.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Bonini Filho, Baumal, Witkin, Reichel.
Critical revision of the manuscript for important intellectual content: Bonini Filho, de Carlo, Ferrara, Adhi, Baumal, Witkin, Duker, Waheed.
Obtained funding: Duker, Waheed.
Administrative, technical, or material support: de Carlo, Witkin, Duker, Waheed.
Study supervision: Ferrara, Baumal, Witkin, Reichel, Duker, Waheed.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Duker is a consultant for and receives research support from Carl Zeiss Meditech Inc and OptoVue Inc. Dr Ferrara is an employee of Genentech Inc. No other disclosures were reported.
Funding/Support: This work was supported in part by an unrestricted grant from Research to Prevent Blindness received by the New England Eye Center/Department of Ophthalmology, Tufts University School of Medicine; grants R01-EY11289, R01-EY013178, and R01-CA075289-16 from the National Institutes of Health; and the Massachusetts Lions Club.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.