Submitted for Publication: January 27, 2015; final revision received April 13, 2015; accepted April 19, 2015.
Published Online: June 4, 2015. doi:10.1001/jamaophthalmol.2015.1700.
Study concept and design: Basilius, Michaelis, Hobbs, Hartnett.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Basilius, Young, Michaelis, Jenkins, Hartnett.
Critical revision of the manuscript for important intellectual content: Basilius, Young, Michaelis, Hobbs, Hartnett.
Statistical analysis: Basilius.
Obtained funding: Hartnett.
Administrative, technical, or material support: Michaelis, Jenkins, Hartnett.
Study supervision: Basilius, Michaelis, Hobbs, Hartnett.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: This work was supported by an unrestricted grant from Research to Prevent Blindness to the Department of Ophthalmology and Visual Sciences, University of Utah, and grant R01 EY015130 from the National Eye Institute (principal investigator, Dr Hartnett).
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: David Dries, MD, and Robert Hoffman, MD, Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, provided clinical input regarding patients 2 and 4; they are supported by departmental funding from Research to Prevent Blindness.