This case report describes separate uveal melanomas in the same eye.
Multiple uveal melanomas (UMs) in the same eye with genetic analysis of each tumor are rarely reported.1 We present a case of 2 distinct UMs with differing molecular alterations in the same eye.
Article InformationCorresponding Author: Sarah E. Coupland, MBBS, PhD, FRCPath, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Daulby Street, Sixth Floor, Duncan Bldg, Liverpool L69 3GA, England (email@example.com).
Published Online: June 25, 2015. doi:10.1001/jamaophthalmol.2015.1962.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Additional Contributions: Sophie Thornton, BSc, Liverpool John Moores University, Liverpool, England, provided technical assistance with this case, in particular, the multiplex ligation-dependent probe amplification analyses and the organization of the GNAQ/11 sequencing; she did not receive compensation for these contributions.