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Ophthalmic Images |

Moniliform Blepharosis of Lipoid Proteinosis Online Only

Michel J. Belliveau, MD1; Alaa Alkhotani, MD2; Asim Ali, MD1,3
[+] Author Affiliations
1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada
2Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
3The Hospital for Sick Children, Toronto, Ontario, Canada
JAMA Ophthalmol. 2015;133(7):e150688. doi:10.1001/jamaophthalmol.2015.0688.
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Two brothers (both younger than 13 years) were evaluated for eyelid margin lesions (Figure). Lesions were present on all 4 lids in both boys. The lesions were itchy and did not respond to steroid or antibiotic therapy. Demodex test results were negative and tea tree oil was ineffective. A full-thickness eyelid biopsy showed dense deposits of eosinophilic hyaline material in the dermis. The lesions are examples of the moniliform blepharosis of lipoid proteinosis.

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Confluent pearly elevations surrounding the base of the cilia.

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Moniliform Blepharosis of Lipoid Proteinosis. JAMA Ophthalmol 2015;133(7):e150688.