Investigators from California and Chicago determine the demographic and geographic variations in vision impairment (VI) and blindness in adults in the US population in 2015 and estimate the projected prevalence through 2050. In 2015, a total of 1.02 million people were blind, and approximately 3.22 million people had VI, whereas up to 8.2 million people had VI due to uncorrected refractive error. Varma and coauthors found that by 2050, the numbers of these conditions are projected to double to approximately 2.01 million people with blindness, 6.95 million people with VI, and 16.4 million with VI due to uncorrected refractive error. The highest numbers of these conditions in 2015 were among non-Hispanic white individuals (2.28 million), women (1.84 million), and older adults (1.61 million), and these groups will remain the most affected through 2050. However, African American individuals experience the highest prevalence of VI and blindness.