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Comment & Response |

Institutional Conflict of Interest ONLINE FIRST

Jean Bennett, MD, PhD1,2,3
[+] Author Affiliations
1Center for Advanced Retinal and Ocular Therapeutics, University of Pennsylvania, Philadelphia
2F. M. Kirby Center for Molecular Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia
3University of Pennsylvania Perelman School of Medicine, Philadelphia
JAMA Ophthalmol. Published online September 01, 2016. doi:10.1001/jamaophthalmol.2016.3248
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To the Editor I read with interest the Viewpoint by McKinney.1 Although its focus is on institutional conflict of interest, I want to comment on my role, as well as the integrity of the study. Dr McKinney, a data safety monitoring committee member for a competing clinical trial, stated that I worked at the Children’s Hospital of Philadelphia (CHOP) when the reagent was invented. This is incorrect. I have been employed at the University of Pennsylvania and do not receive any salary from CHOP. The construct used to generate the recombinant virus was created in my laboratory and incorporated complementary DNA that we cloned prior to any interaction with CHOP. My association with CHOP is one of scientific collaboration on clinical trials initially sponsored by CHOP and now supported by Spark Therapeutics through a Clinical Trials Agreement.


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September 1, 2016
Ross E. McKinney Jr, MD
1Department of Pediatrics, Duke University Medical Center, Durham, North Carolina
JAMA Ophthalmol. Published online September 01, 2016.;():. doi:10.1001/jamaophthalmol.2016.3250.
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