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Conjunctival Aluminum Deposition Following Pneumatic Cryopexy

Eric J. Linebarger, MD; Don O. Kikkawa, MD; Bessie Floyd, MD; David Granet, MD; Marc Booth, MD
Arch Ophthalmol. 1999;117(5):692-693. doi:10.1001/archopht.117.5.692.
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A 76-YEAR-OLD man with a history of multiple cutaneous melanomas was referred to our institution after noticing a gradually enlarging pigmented mass in his right eye. The patient underwent successful pneumatic cryopexy of a retinal tear in the temporal region of the right eye 4 years previously with no reported complications. He denied any other prior ocular trauma or surgery.

Visual acuity was 20/20 OU with normal intraocular pressures. Ocular motility examination revealed full ductions and orthophoria. Slitlamp examination revealed a 4×2-mm, elevated, darkly pigmented conjunctival mass surrounding the insertion site of the lateral rectus (Figure 1). Increased vascularization was also noted around the area of involvement. In view of the patient's history of multiple prior cutaneous melanomas and the highly suspicious nature of the lesion, an excisional biopsy was performed.

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Figure 1.

External view of lateral conjunctiva of right eye showing pigmented mass.

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Figure 2.

Low-power photomicrograph showing diffuse pigment deposition throughout the conjunctival stroma (hematoxylin-eosin, original magnification ×40).

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Figure 3.

High-power photomicrograph showing perivascular granular pigment. No cellular atypia was noted (hematoxylin-eosin, original magnification ×400).

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Figure 4.

Energy dispersive analysis of x-rays (EDAX) showing strong peak corresponding to aluminum (Al) and trace amounts of silicone (Si).

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