The clinical variables included patient age, race (Caucasian†, African American), sex (male†, female), eye (right†, left), signs and symptoms (spot†, lump, irritation, other, none), medical history (cutaneous melanoma, dysplastic nevus syndrome, uveal melanoma, neurofibromatosis, acquired immunodeficiency syndrome, and others), family history (conjunctival melanoma, cutaneous melanoma, dysplastic nevus syndrome, uveal melanoma, neurofibromatosis, and others), cutaneous complexion (fair white†, olive white, nonwhite), and prior systemic treatment (chemotherapy, corticosteroids, ocular radiation). Prior management of the tumor before referral was assessed for type of surgical technique (incisional biopsy, excisional biopsy†, cryotherapy, alcohol corneal epitheliectomy) and number of prior recurrences. The general ocular clinical features included visual acuity, iris color (blue†, green, brown), eyelid lentigo maligna (present, absent†), and associated PAM and its extent (number of clock hours involved). The tumor features at initial patient visit included melanoma quadrant location (superior, nasal, inferior, lateral†, diffuse), melanoma anatomic conjunctival location (bulbar†, fornix, tarsus, plica semilunaris, caruncle), melanoma bulbar extension (number of clock hours involved), melanoma proximity to limbus (in millimeters), radial corneal involvement by melanoma (in millimeters), and depth of corneal involvement by melanoma (epithelium†, stroma, Descemet membrane). Additional clinical tumor features included melanoma base size (in millimeters), melanoma thickness (in millimeters), melanoma color (brown†, red, yellow, variable), melanoma feeder vessels (present, absent†), initial tumor surgery after referral (incisional biopsy, excisional biopsy†, cryotherapy, alcohol corneal epitheliectomy, exenteration), local melanoma recurrence (number), eventual orbital exenteration (yes, no†), and final visual acuity. Melanoma recurrence was defined as the development of a new histopathologically confirmed malignant melanoma at any site on the conjunctiva or ocular adnexa after prior surgical treatment. The site of recurrence could be the same or different than prior tumors. Histopathologically proven melanoma metastasis and melanoma-related death was recorded.