First, we performed age-adjusted analyses relating progression to each obesity measurement at baseline, after controlling for the following age-sex groups coded as dummy variables: men aged 60 to 69 years, men aged 70 to 79 years, men 80 years and older, women aged 60 to 69 years, women aged 70 to 79 years, and women 80 years and older. The Cox proportional hazards model was used to estimate relative risks (RRs) for progression adjusting for additional risk factors. Specifically, we used the SAS Procedure PHREG (SAS Institute Inc, Cary, NC) to relate time to AMD progression to anthropomorphic factors(BMI, waist circumference, and waist-hip ratio at baseline) in separate analyses while controlling for the age-sex group, physical activity (times per week of vigorous activity as a continuous variable), cigarette smoking status (current, past, or never), systolic blood pressure (analyzed continuously in 10-mmHgincrements), baseline AMD grade in the worst eye (categorical), education(at least high school vs less than high school), log calories, calorie-adjusted carotenoid intake, and alcohol intake. We divided BMI into 3 categories (<25, 25-29, and ≥30). Waist circumferences and waist-hip ratios were divided into tertiles separately for men and women. Variables were entered in 3 regression models separately for BMI, waist circumference, and waist-hip ratio. For each model we performed categorical analyses by comparing each BMI, waist circumference, and waist-hip ratio subgroup with the referent group (typically the lowest category). In addition, we also performed tests for trend by scoring BMI, waist circumference, and waist-hip ratio as ordinal variables, eg, test for trend for BMI was scored as 1 if less than 25; 2 if 25 to 29; and 3 if at least 30. Rates of progression were calculated using the Kaplan-Meier estimator. We used SAS software, version 6.12 (SAS Institute Inc), to perform all analyses.