To describe a method to measure the progression of ocular cicatricialpemphigoid and to compare its facility with traditional methods used to measurethe progression of the disease.
The proposed method consists of measuring (in millimeters) the totalrelative inferior conjunctival surface available in 3 gaze positions. Thismethod was used to monitor 7 eyes of 4 patients with ocular cicatricial pemphigoidover 2 years. The changes in the conjunctival measurements from baseline werecompared with the changes documented by traditional methods.
During the study, 2 eyes remained stable (changes, <3 mm), 2 hada decrease of 10 mm or more, and 3 had a change in measurements between 4and 9 mm. With the proposed method, we demonstrated the detection of moresubtle changes in the conjunctiva of all patients. Patients who had changesbetween 4 and 9 mm easily underwent staging by the traditional systems whenthe new technique was used as a reference.
The proposed method offers an objective variable that can be used inconsecutive visits to detect subtle progression or disease control in patientswith ocular cicatricial pemphigoid.